Uchida T
Department of Pathology I, Nihon University School of Medicine.
Nihon Rinsho. 1993 Feb;51(2):352-6.
Hepatitis E is endemic, often provoking epidemics in many developing countries. The hepatitis E virus has been molecularly cloned and sequenced and has a single-stranded, positive-sense RNA genome, 7,194 nucleotides, followed by a poly(A) tail. There are three open reading frames. The non-structural gene, approximately 5 kb, is located at the 5' end, while the structural gene, approximately 2 kb, is located at the 3' end of the genome. There is low level nucleotide variation among hepatitis E virus strains isolated from Myanmar and China.
戊型肝炎呈地方性流行，在许多发展中国家常常引发疫情。戊型肝炎病毒已被进行分子克隆和测序，其基因组为单链正义RNA，有7194个核苷酸，后面跟着一个聚腺苷酸尾。有三个开放阅读框。非结构基因约5kb，位于基因组的5'端，而结构基因约2kb，位于基因组的3'端。从缅甸和中国分离出的戊型肝炎病毒株之间核苷酸变异水平较低。
