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[获得性免疫缺陷综合征患者合并新型隐球菌性脑膜炎的抗利尿激素分泌不当综合征]

[The inappropriate antidiuretic hormone secretion syndrome associated with cryptococcal meningitis in a patient with the acquired immunodeficiency syndrome].

作者信息

Brea Hernando A I, Bandrés Franco E, Aguirre Miñana T, Ezquerra Lezcano M, Borque de Larrea L

机构信息

Servicio de Medicina Interna, Hospital San Millán, Logroño, La Rioja.

出版信息

Med Clin (Barc). 1993 Mar 20;100(11):420-2.

PMID:8464260
Abstract

Meningitis and other infectious diseases of the central nervous system are predisposing causes of the inadequate secretion syndrome of the antidiuretic hormone (ISADH). The association between the acquired immunodeficiency syndrome (AIDS) and ISADH is recognized but little studied. In AIDS patients hyponatremia is a frequent finding and it is responsible for ISADH in most cases. However, there is little reference material concerning the incidence of presentation and the type of osmoregulation anomaly this entity presents in these patients. A case in which ISADH is associated to cryptococcal meningitis and AIDS is described with an evaluation of the hormonal response to the test of hypertonic saline serum infusion corresponding to a release of ADH.

摘要

脑膜炎及中枢神经系统的其他传染病是抗利尿激素分泌不足综合征(ISADH)的诱发因素。获得性免疫缺陷综合征(AIDS)与ISADH之间的关联已得到认可,但研究较少。在艾滋病患者中,低钠血症很常见,且在大多数情况下是由ISADH引起的。然而,关于这些患者中该病症的发生率以及所呈现的渗透调节异常类型的参考资料很少。本文描述了一例ISADH与隐球菌性脑膜炎及艾滋病相关的病例,并对与抗利尿激素释放相对应的高渗盐水血清输注试验的激素反应进行了评估。

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