el Hassan A M, Hashim F A, Abdullah M, Zijlstra E E, Ghalib H W
Department of Pathology, Faculty of Medicine, University of Khartoum.
Lepr Rev. 1993 Mar;64(1):53-9. doi: 10.5935/0305-7518.19930007.
In this study 4 patients were post-kala-azar dermal leishmaniasis (PKDL), whose lesions were similar to those of lepromatous and borderline leprosy, are described. In 2 patients there was no previous history of kala-azar but they were residents of an area of known endemic kala-azar. Lack of proper clinical and laboratory assessment was behind the failure to diagnose PKDL. Consequently the patients were treated with antileprosy drugs without proof of leprosy. The 3rd and 4th patients, though suspected clinically of leprosy, were correctly diagnosed as PKDL with adequate history, clinical assessment and appropriate laboratory investigations. The salient points in distinguishing PKDL from leprosy are described and discussed.
本研究描述了4例黑热病后皮肤利什曼病（PKDL）患者，其皮损与瘤型麻风及界线类麻风相似。2例患者既往无黑热病病史，但他们居住在已知黑热病流行地区。未能诊断出PKDL是由于缺乏适当的临床和实验室评估。因此，这些患者在未确诊麻风的情况下接受了抗麻风药物治疗。第3例和第4例患者，尽管临床怀疑为麻风，但通过充分的病史、临床评估和适当的实验室检查被正确诊断为PKDL。文中描述并讨论了鉴别PKDL与麻风的要点。
