Gerasimova I A, Emel'yanov M A, Mokrushin A A, Pavlinova L I
Laboratory of the Regulation of Functions of Brain Neurons, I.P. Pavlov Institute of Physiology, Russian Academy of Sciences, Leningrad.
Neurosci Behav Physiol. 1993 Jan-Feb;23(1):63-5. doi: 10.1007/BF01182640.
It was demonstrated that a decrease in the intensity of methylation of phosphatidylethanolamine in sections of rat olfactory cortex is observed 15 min following the introduction of picrotoxin (10(-5) M) into the incubation medium. The decrease in the intensity of methylation of phospholipids may be closely linked to the opening of ion channels, since it is known that maximal depolarization of the membranes is observed during this period of the effect of the preparation.
已证明，在将印防己毒素（10^(-5) M）引入孵育介质15分钟后，观察到大鼠嗅觉皮质切片中磷脂酰乙醇胺甲基化强度降低。磷脂甲基化强度的降低可能与离子通道的开放密切相关，因为已知在制剂作用的这一时期观察到膜的最大去极化。
