Olsen K D, Thomas J V, DeSanto L W, Suman V J
Department of Otorhinolaryngology, Mayo Clinic, Rochester, MN 55905.
Otolaryngol Head Neck Surg. 1993 Mar;108(3):277-82. doi: 10.1177/019459989310800312.
Select early glottic carcinomas in patients with normal vocal cord mobility can be successfully treated with cordectomy, performed either endoscopically or by means of an open operation (laryngofissure-cordectomy). From 1976 to 1986, 95 patients underwent cordectomy at our institution. There were 88 men and 7 women, with an age range at the time of surgery of 27 to 84 years. A laryngofissure was used to perform a cordectomy in 61 patients and an endoscopic approach was used in 34. The median number of days in the hospital for the endoscopic group was 2, and for the laryngofissure group it was 6. The Kaplan-Meier product-limit method showed the probability of no recurrence in the first 3 years after an endoscopic cordectomy was 0.9099, and in the laryngofissure-cordectomy group it was 0.9502. To date, there have been four recurrences (11.8%) in the endoscopic group and three (4.9%) in the laryngofissure group. Only one patient with recurrent tumor is known to have died of the cancer. Laryngectomy was necessary for ultimate control in three patients. The Kaplan-Meier survival curve for the 95 patients was the same as that for a sex- and age-matched control group. Cordectomy is an effective treatment option that results in minimal morbidity for select early glottic carcinomas.
对于声带活动正常的早期声门癌患者，可通过内镜下或开放性手术（喉裂开-声带切除术）成功进行声带切除术治疗。1976年至1986年，我院有95例患者接受了声带切除术。其中男性88例，女性7例，手术时年龄范围为27至84岁。61例患者采用喉裂开进行声带切除术，34例采用内镜入路。内镜组的中位住院天数为2天，喉裂开组为6天。Kaplan-Meier乘积限界法显示，内镜下声带切除术后前3年无复发的概率为0.9099，喉裂开-声带切除术组为0.9502。迄今为止，内镜组有4例复发（11.8%），喉裂开组有3例（4.9%）。已知仅1例复发肿瘤患者死于癌症。3例患者最终需要行喉切除术以控制病情。95例患者的Kaplan-Meier生存曲线与性别和年龄匹配的对照组相同。声带切除术是一种有效的治疗选择，对于特定的早期声门癌，其发病率极低。
