Mayes L C, Granger R H, Frank M A, Schottenfeld R, Bornstein M H
Yale Child Study Center, New Haven, CT 06510.
Pediatrics. 1993 Apr;91(4):778-83.
This study examined the effects of maternal cocaine use on performance on the Neonatal Behavioral Assessment Scale (NBAS). Cocaine-exposed newborns (n = 56) were compared with a non-cocaine-exposed group (n = 30) born to mothers with similar sociodemographic characteristics. Cocaine-exposed newborns showed significant reduction in birth weight but did not experience greater obstetric or postnatal complications. On neurobehavioral assessments using the NBAS, cocaine-exposed newborns showed significantly depressed performance on the habituation cluster but not on other NBAS clusters when differences in birth weight were controlled. In a sample of 30 cocaine-exposed newborns matched on birth weight, gestational age, and race to the 30 non-cocaine-exposed newborns, cocaine-exposed newborns continued to show depressed habituation performance. The significance of a selective effect of cocaine exposure on early habituation performance is discussed in terms of the implications for attentional regulation in the first year of life.
本研究考察了母亲使用可卡因对新生儿行为评估量表（NBAS）表现的影响。将暴露于可卡因的新生儿（n = 56）与社会人口统计学特征相似的母亲所生的非可卡因暴露组（n = 30）进行比较。暴露于可卡因的新生儿出生体重显著降低，但未经历更多的产科或产后并发症。在使用NBAS进行神经行为评估时，当控制出生体重差异后，暴露于可卡因的新生儿在习惯化集群上的表现显著下降，但在其他NBAS集群上没有。在一个由30名出生体重、胎龄和种族与30名非可卡因暴露新生儿匹配的暴露于可卡因的新生儿样本中，暴露于可卡因的新生儿继续表现出习惯化表现下降。从对生命第一年注意力调节的影响方面讨论了可卡因暴露对早期习惯化表现的选择性作用的重要性。
