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[高血压中的左心室肥厚是冠状动脉危险因素的标志物吗?]

[Is left ventricular hypertrophy in hypertension a marker for coronary risk factors?].

作者信息

Otterstad J E

机构信息

Kardiologisk seksjon, Medisinsk avdeling, Vestfold sentralsykehus, Tønsberg.

出版信息

Tidsskr Nor Laegeforen. 1993 Feb 20;113(5):609-13.

PMID:8465321
Abstract

86 asymptomatic men with mild to moderate hypertension were examined by echocardiography, exercise ECG and measurements of their lipid profile. Left ventricular hypertrophy, defined as an increased left ventricular mass index > or = 130 g/m2, was found in 38 (44%) patients. Only two men showed evidence of silent ischemia during maximum exercise. The men with left ventricular hypertrophy had a higher systolic blood pressure at rest (p = 0.0002), at submaximal (p = 0.02) and maximal exercise (p = 0.01). The prevalence of smokers was the same, as were the concentrations of lipids, lipoproteins and apoproteins in the two groups. Except for a higher blood pressure, left ventricular hypertrophy is not a special marker for other coronary risk factors.

摘要

对86名患有轻度至中度高血压的无症状男性进行了超声心动图、运动心电图检查以及血脂水平测量。左心室肥厚定义为左心室质量指数增加≥130 g/m²,在38名(44%)患者中被发现。只有两名男性在最大运动量时显示出无症状性心肌缺血的迹象。左心室肥厚的男性在静息时(p = 0.0002)、次最大运动量时(p = 0.02)和最大运动量时(p = 0.01)的收缩压更高。两组吸烟者的患病率相同,血脂、脂蛋白和载脂蛋白的浓度也相同。除了血压较高外,左心室肥厚并非其他冠状动脉危险因素的特殊标志物。

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