Grantham-McGregor S M, Walker S P, Himes J H, Powell C A
Tropical Metabolism Research Unit, University of the West Indies, Mona, Jamaica.
Trans R Soc Trop Med Hyg. 1993 Jan-Feb;87(1):109-13. doi: 10.1016/0035-9203(93)90448-y.
Infection and undernutrition in young children are thought to act synergistically. However, studies of the relationship between low height-for age (stunting) and morbidity in young children have had inconsistent findings and there are few adequate data on the effects of nutritional supplementation on morbidity. 129 stunted and 21 non-stunted children aged between 9 and 24 months, from poor Kingston neighbourhoods, identified from a house-to-house survey, were studied. The stunted children were randomly assigned to supplementation or no supplementation. Every week for 24 months the mothers were asked about the occurrence of any symptoms of illness. Supplementation had no consistent effect on the incidence or duration of symptoms. The stunted children had significantly more attacks of diarrhoea, fever, anorexia and apathy than the non-stunted children. The differences remained after controlling for social background and previous attacks of diarrhoea. There was also some indication of more severe illness in the stunted than in the non-stunted children.
幼儿期的感染与营养不良被认为具有协同作用。然而，关于年龄别身高偏低（发育迟缓）与幼儿发病率之间关系的研究结果并不一致，而且关于营养补充对发病率影响的充分数据也很少。我们对通过逐户调查从金斯敦贫困社区确定的129名9至24个月大的发育迟缓儿童和21名非发育迟缓儿童进行了研究。发育迟缓儿童被随机分为补充组或非补充组。在24个月的时间里，每周都会询问母亲孩子是否出现任何疾病症状。补充营养对症状的发生率或持续时间没有一致的影响。发育迟缓儿童的腹泻、发烧、厌食和冷漠发作明显多于非发育迟缓儿童。在控制了社会背景和既往腹泻发作情况后，这些差异仍然存在。还有一些迹象表明，发育迟缓儿童的病情比非发育迟缓儿童更严重。
