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混合性食道口线虫和钩虫感染的治疗:阿苯达唑、噻嘧啶、左旋咪唑和噻苯达唑的疗效

Treatment of mixed Oesophagostomum and hookworm infection: effect of albendazole, pyrantel pamoate, levamisole and thiabendazole.

作者信息

Krepel H P, Haring T, Baeta S, Polderman A M

机构信息

Ministry of Health, Dapaong, Togo.

出版信息

Trans R Soc Trop Med Hyg. 1993 Jan-Feb;87(1):87-9. doi: 10.1016/0035-9203(93)90437-u.

DOI:10.1016/0035-9203(93)90437-u
PMID:8465409
Abstract

Oesophagostomum bifurcum has recently been recognized as a common parasite of man in northern Togo and in Ghana. In a preliminary trial several anthelmintics were evaluated in the treatment of mixed Oesophagostomum and hookworm infections. Diagnosis was based on faecal culture, since the eggs of Oesophagostomum and hookworm cannot be distinguished morphologically. Of the anthelmintics tested, albendazole was most effective against both parasites. Pyrantel pamoate, 2 x 10 mg/kg, was effective against Oesophagostomum but not against hookworm. The cure rates for both parasites were moderate with thiabendazole and poor with levamisole.

摘要

分叉食道口线虫最近被认为是多哥北部和加纳人类的一种常见寄生虫。在一项初步试验中,对几种驱虫药在治疗食道口线虫和钩虫混合感染方面进行了评估。诊断基于粪便培养,因为食道口线虫和钩虫的卵在形态上无法区分。在所测试的驱虫药中,阿苯达唑对这两种寄生虫最有效。2×10毫克/千克的双羟萘酸噻嘧啶对食道口线虫有效,但对钩虫无效。噻苯达唑对两种寄生虫的治愈率中等,左旋咪唑的治愈率较低。

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