Hausdorf G, Schneider M, Schirmer K R, Uhlemann F, Will J C, Loebe M, Hetzer R, Lange P E
Abteilung Angeborene Herzfehler/Kinderkardiologie, Deutsches Herzzentrum Berlin.
Z Kardiol. 1993 Feb;82(2):123-30.
In 18 patients with pulmonary atresia interventional perforation of the atresia was attempted using radiofrequency. All patients were referred for palliative surgery. The age ranged from 4 days to 19 years. After angiographic delineation of the relations between the right ventricular outflow tract and main pulmonary artery the tip of a radiofrequency perforation catheter (Cerablate-catheter, 2F, Osypka) was brought into contact with the atresia. The radiofrequency was applied in the unipolar fashion (radiofrequency-generator HAT 200, Osypka). Radiofrequency perforation was successfully performed in 14/18 patients, subsequent balloon dilatation was performed in 12 of these patients. In six patients with muscular atresia a Palmaz-stent was implanted into the right ventricular outflow tract. An inadvertent perforation of the right ventricular outflow tract occurred in three patients, of the pulmonary artery in two patients. However, these were tolerated without sequelae or clinical symptoms. The arterial oxygen saturation increased by 21%; in none of the patients was cardiac failure or pulmonary edema observed. Using the Cerablate-catheter even muscular atresias could be perforated. Implantation of a stent into the newly created right ventricular outflow tract results in a predictable communication between the right ventricle and the pulmonary artery. Although this interventional right ventricular outflow tract creation seems to be a promising new technique, experience is limited and there are no long-term results.
对18例肺动脉闭锁患者尝试使用射频进行闭锁部位的介入性穿孔。所有患者均被转诊接受姑息性手术。年龄范围为4天至19岁。在通过血管造影明确右心室流出道与主肺动脉之间的关系后,将一根射频穿孔导管(Cerablate导管,2F,奥西卡公司)的尖端与闭锁部位接触。以单极方式施加射频(射频发生器HAT 200,奥西卡公司)。18例患者中有14例成功进行了射频穿孔,其中12例随后进行了球囊扩张。6例肌肉型闭锁患者在右心室流出道植入了帕尔马兹支架。3例患者右心室流出道发生意外穿孔,2例患者肺动脉发生意外穿孔。然而,这些穿孔均未引起后遗症或临床症状。动脉血氧饱和度提高了21%;所有患者均未观察到心力衰竭或肺水肿。使用Cerablate导管甚至可以对肌肉型闭锁进行穿孔。在新形成的右心室流出道植入支架可使右心室与肺动脉之间建立可预测的连通。尽管这种介入性右心室流出道创建似乎是一种有前景的新技术,但经验有限且尚无长期结果。