人上颌窦鳞状细胞癌中的核仁组织区

Nucleolar organizer regions in human maxillary sinus squamous cell carcinoma.

作者信息

Kuwabara H, Miyaguchi M, Uda H, Krenåcs T, Sepp R, Sakai S

机构信息

Department of Pathology, Kagawa Medical School, Japan.

出版信息

Acta Pathol Jpn. 1993 Jan-Feb;43(1-2):18-21. doi: 10.1111/j.1440-1827.1993.tb02909.x.

DOI:10.1111/j.1440-1827.1993.tb02909.x

PMID:8465651

Abstract

A silver colloid technique for nucleolar organizer regions (AgNOR) was applied to paraffin sections of maxillary sinus squamous cell carcinomas (MSSCC) of 25 patients. The patients were divided into two groups, one with MSSCC recurring in the primary lesion after treatment with radiotherapy, chemotherapy and/or surgery and one without recurrence. Notable differences between the numbers of NOR in neoplastic epithelia and the normal mucosa were observed (P = 0.0001), but there were no differences between the numbers of NOR in the recurrent and non-recurrent carcinomas. This investigation found no prognostic importance in the number of AgNOR in MSSCC.

摘要

一种用于核仁组织区（AgNOR）的银胶体技术应用于25例上颌窦鳞状细胞癌（MSSCC）患者的石蜡切片。患者分为两组，一组是经放疗、化疗和/或手术治疗后原发灶复发的MSSCC患者，另一组是未复发的患者。观察到肿瘤上皮细胞和正常黏膜中NOR数量存在显著差异（P = 0.0001），但复发癌和未复发癌的NOR数量之间没有差异。本研究发现MSSCC中AgNOR数量没有预后意义。