Søndergaard L, Lindvig K, Hildebrandt P, Thomsen C, Ståhlberg F, Joen T, Henriksen O
Danish Research Centre of Magnetic Resonance, Hvidovre Hospital, University of Copenhagen.
Am Heart J. 1993 Apr;125(4):1081-90. doi: 10.1016/0002-8703(93)90117-r.
The use of magnetic resonance (MR) velocity mapping in the quantification of aortic valvular blood flow was examined in 10 patients with angiographically verified aortic regurgitation. MR velocity mapping succeeded in identifying and quantifying the regurgitation in all patients, and the regurgitant volume determined with MR velocity mapping agreed well with the grade obtained by aortic root angiography (p < 0.02). The accuracy in quantification of the aortic valvular flow rate was demonstrated by a significant correlation between the stroke volume (ml) measured by MR velocity mapping and calculated from MR imaging of the left ventricular end-diastolic and end-systolic volumes in eight patients (Y = 0.89 x X + 11, r = 0.97, p < 0.001). This finding was confirmed by a good agreement between the net cardiac output (L/min) quantified with MR velocity mapping and simultaneous 125I-indicator dilution measurement in all subjects (Y = 0.89 x X + 0.08, r = 0.82, p < 0.01). In conclusion, MR velocity mapping may be used as a noninvasive tool in the quantification of aortic regurgitation.
对10例经血管造影证实有主动脉瓣反流的患者，研究了磁共振（MR）速度图在主动脉瓣血流定量分析中的应用。MR速度图成功识别并量化了所有患者的反流情况，通过MR速度图测定的反流容积与经主动脉根部血管造影获得的分级结果高度一致（p < 0.02）。8例患者中，通过MR速度图测量的每搏输出量（ml）与根据左心室舒张末期和收缩末期容积的MR成像计算得出的结果之间存在显著相关性，证明了MR速度图在主动脉瓣流速定量分析中的准确性（Y = 0.89 x X + 11，r = 0.97，p < 0.001）。所有受试者中，通过MR速度图量化的净心输出量（L/min）与同时进行的125I指示剂稀释测量结果高度一致，证实了这一发现（Y = 0.89 x X + 0.08，r = 0.82，p < 0.01）。总之，MR速度图可作为一种无创工具用于主动脉瓣反流的定量分析。
