超抗原在自身免疫中起作用吗？
Do superantigens play a role in autoimmunity?
作者信息
Posnett D N
机构信息
Cornell University Medical College, New York, NY 10021.
出版信息
Semin Immunol. 1993 Feb;5(1):65-72. doi: 10.1006/smim.1993.1009.
PMID:8467097
Abstract
Mycoplasma arthritidis produces a typical soluble superantigen (SAg) which shares many characteristics with bacterial toxins and Mouse Mammary Tumor Virus SAg. However, this microbe is associated with an autoimmune-like disorder and this disease may therefore serve as a model to investigate the potential role of a SAg in autoimmune disease pathogenesis.
摘要
关节炎支原体产生一种典型的可溶性超抗原（SAg），它与细菌毒素和小鼠乳腺肿瘤病毒SAg有许多共同特征。然而，这种微生物与一种自身免疫样疾病有关，因此这种疾病可作为研究SAg在自身免疫性疾病发病机制中潜在作用的模型。
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