Murakami S, Yashuda S, Nakamura T, Mishima Y, Iida H, Okano H, Nakano M
Second Department of Surgery, Tokyo Medical and Dental University, Japan.
Surg Today. 1993;23(2):153-8. doi: 10.1007/BF00311234.
Metastatic lesions from renal cell carcinoma are commonly recognized in the lung and bone, however, thyroid metastasis has rarely been reported in the literature. We present herein a case of a man with lung and thyroid metastatic tumors from renal cell carcinoma. Although making a preoperative diagnosis of thyroid metastasis is difficult because there is no established diagnostic criteria, we were able to identify this thyroid lesion as a metastatic tumor from renal cell carcinoma by the pathological findings. Interestingly, hypercalcemia was recognized in this patient whose serum parathyroid hormone (PTH) level was not increased. Moreover, this patient also had early gastric cancer simultaneously, being a so-called 'double cancer'. After surgical resection of the right kidney and stomach, interferon was administered without any efficacy against the metastatic lesions of the lung and thyroid gland.
肾细胞癌的转移病灶常见于肺和骨,然而,甲状腺转移在文献中鲜有报道。我们在此报告一例患有肾细胞癌肺和甲状腺转移瘤的男性病例。尽管由于没有既定的诊断标准,术前诊断甲状腺转移很困难,但通过病理检查结果,我们能够确定该甲状腺病变为肾细胞癌转移瘤。有趣的是,该患者血钙升高,而血清甲状旁腺激素(PTH)水平并未升高。此外,该患者同时还患有早期胃癌,即所谓的“双癌”。在手术切除右肾和胃后,给予干扰素治疗,但对肺和甲状腺的转移病灶无效。