杜兴氏肌营养不良症携带者中肌营养不良蛋白染色的单盲研究。
Single-blind study of dystrophin staining in carriers of Duchenne muscular dystrophy.
作者信息
Bernier F P, Greenberg C R, Halliday W C, Wrogemann K
机构信息
Department of Pediatrics & Child Health, University of Manitoba, Winnipeg, Canada.
出版信息
Can J Neurol Sci. 1993 Feb;20(1):44-7. doi: 10.1017/s0317167100047399.
A single-blind study of dystrophin staining in skeletal muscle was performed in 13 biopsies from carriers of Duchenne Muscular Dystrophy (DMD) and controls. The results indicate that immunohistochemical analysis of dystrophin staining is a valuable diagnostic test for DMD carriers when DNA for testing is unavailable from critical family members or is uninformative, when creatine kinase (CK) values are conflicting or when CK values must be used in isolation.
对13例来自杜氏肌营养不良症（DMD）携带者及对照者的骨骼肌活检样本进行了肌营养不良蛋白染色的单盲研究。结果表明，当无法从关键家庭成员获取用于检测的DNA或检测结果无信息价值时，当肌酸激酶（CK）值相互矛盾时，或当必须单独使用CK值时，肌营养不良蛋白染色的免疫组织化学分析是DMD携带者的一项有价值的诊断测试。
Zotero 插件