Sautter-Bihl M L, Liebermeister E, Scheurig H, Heinze H G
Klinik für Strahlentherapie und Nuklearmedizin, Städtisches Klinikum Karlsruhe.
Dtsch Med Wochenschr. 1993 Apr 8;118(14):493-8. doi: 10.1055/s-2008-1059354.
Between 1980 and 1991, ionizing radiation was applied for analgesic purposes to 181 patients (97 men, 84 women, mean age 54 [29-81] years) with degenerative-inflammatory skeletal disease. The long-term effects were evaluated by questionnaire. Radiation of 2.5 to 6.0 Gy achieved lasting pain relief in 21 of 30 patients (70%) with arthritis of the shoulder or humeroscapular periarthritis, 15 of 21 (71%) with arthritis of the hip, in 12 of 15 (80%) with heel spurs or Achilles tendon bursitis and 10 of 11 (91%) with epicondylitis. Pain relief lasted for longer than two years in 41 of the 77 patients (53%). There were no side effects at the stated dosage. According to dose measurements the theoretical risk of malignant tumour induction is 20-40/million radiated patients and thus four orders of magnitude below the spontaneous malignant tumour incidence rate. The genetic risk is even lower. Ionizing radiation of degenerative-inflammatory diseases is thus an effective form of treatment with few side effects.
1980年至1991年间，对181例患有退行性炎症性骨骼疾病的患者（97名男性，84名女性，平均年龄54[29 - 81]岁）进行了电离辐射以达到止痛目的。通过问卷调查评估长期效果。2.5至6.0戈瑞的辐射使30例肩部关节炎或肩周炎患者中的21例（70%）、21例髋关节炎患者中的15例（71%）、15例跟骨刺或跟腱滑囊炎患者中的12例（80%）以及11例肱骨外上髁炎患者中的10例（91%）实现了持久的疼痛缓解。77例患者中有41例（53%）的疼痛缓解持续超过两年。在规定剂量下未出现副作用。根据剂量测量，诱发恶性肿瘤的理论风险为每百万接受辐射的患者20 - 40例，因此比自发恶性肿瘤发病率低四个数量级。遗传风险甚至更低。因此，对退行性炎症性疾病进行电离辐射是一种有效的治疗方式，副作用很少。
