Krauss T, Rath W, Kuhn W
Universitäts-Frauenklinik Göttingen.
Geburtshilfe Frauenheilkd. 1993 Mar;53(3):194-7. doi: 10.1055/s-2007-1023664.
The frequency of abruptio placentae has nearly tripled in our clinic since 1974 and now stands at 1.4% of all deliveries. In a retrospective analysis it was investigated whether improved diagnostic and therapeutic methods have decreased the morbidity and mortality of this severe obstetrical complication. During 3 stages of observation--1974-1979, 1980-1985 and 1986-6/1990--we registered 123 cases. The division into time intervals was based on the introduction of sensitive ultrasonic methods in 1980 and the vaginal scan in 1986. Important risk factors of abruptio placentae were found to be bleeding in pregnancy (32%), previous curettages (38%), premature labour (29%), and pre-eclampsia (14%). The diagnostic sensitivity of sonography rose from 40% in the first to 78% in the third interval of observation. The rate of vaginal deliveries decreased from 15% to 2%. Simultaneously, the perinatal mortality decreased, despite increasing foetal prematurity, from 30% to 2%. The improvement in foetal outcome could be demonstrated by 1- and 5-minute Apgar score values. During the entire period, we lost one mother with abruptio placentae complicated by fulminant lung embolism intra operationem. The frequency of serious stages of abruptio placentae (Page 2-3) decreased from 69% to 33%. While 54% of the mothers developed shock (shock index > or = 1) during delivery in the first observation period, this figure was finally only 10.5%. At the same time the frequency of coagulation disorders decreased from 31% to 4%.
自1974年以来,我院胎盘早剥的发生率几乎增加了两倍,目前占所有分娩的1.4%。通过回顾性分析,研究了诊断和治疗方法的改进是否降低了这种严重产科并发症的发病率和死亡率。在三个观察阶段——1974 - 1979年、1980 - 1985年和1986 - 1990年6月——我们记录了123例病例。划分为不同时间段是基于1980年引入敏感超声方法以及1986年引入阴道超声。发现胎盘早剥的重要危险因素有孕期出血(32%)、既往刮宫史(38%)、早产(29%)和先兆子痫(14%)。超声检查的诊断敏感性从第一观察阶段的40%升至第三观察阶段的78%。阴道分娩率从15%降至2%。同时,尽管胎儿早产率增加,但围产儿死亡率从30%降至2%。胎儿结局的改善可通过1分钟和5分钟阿氏评分来证明。在整个期间,我们有1例胎盘早剥的母亲在手术中并发暴发性肺栓塞死亡。胎盘早剥严重阶段(第2 - 3页)的发生率从69%降至33%。在第一个观察阶段,54%的母亲在分娩时发生休克(休克指数≥1),而最终这一数字仅为10.5%。同时,凝血障碍的发生率从31%降至4%。