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AB023,新型多烯抗生素。II. 分离与结构测定。

AB023, novel polyene antibiotics. II. Isolation and structure determination.

作者信息

Bortolo R, Spera S, Gugliemetti G, Cassani G

机构信息

Istituto Guido Donegani, ENICHEM, Novara, Italy.

出版信息

J Antibiot (Tokyo). 1993 Feb;46(2):255-64. doi: 10.7164/antibiotics.46.255.

Abstract

AB023, a complex of new polyene antibiotics, was isolated from a soil Streptomyces strain. The two main components, pentaene antibiotics AB023a and AB023b, were separated and purified by preparative chromatographic methods and their structures were determined by extensive NMR and mass spectrometric studies.

摘要

AB023是一种新型多烯抗生素复合物,从一株土壤链霉菌中分离得到。通过制备色谱法分离并纯化了两种主要成分,即五烯抗生素AB023a和AB023b,并通过广泛的核磁共振和质谱研究确定了它们的结构。

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