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精神分裂症患者的阴性症状和情感迟钝

Negative symptoms and emotional blunting in schizophrenic patients.

作者信息

de Leon J, Peralta V, Cuesta M J

机构信息

Medical College of Pennsylvania, Eastern Pennsylvania Psychiatric Institute, Philadelphia 19129.

出版信息

J Clin Psychiatry. 1993 Mar;54(3):103-8.

PMID:8468308
Abstract

BACKGROUND

Emotional blunting and negative symptoms were explored as interchangeable concepts in evaluating schizophrenic patients.

METHOD

We evaluated 115 consecutively admitted patients who had DSM-III-R schizophrenia. We performed a principal component analysis of Abrams and Taylor's Scale for Emotional Blunting (SEB) and Andreasen's Scale for the Assessment of Negative Symptoms (SANS) and correlated the subscales derived by factor analyses with demographic and clinical variables.

RESULTS

Both scales contained subscales corresponding to poverty of affect and speech and inappropriate affect. The SEB also included an indifference subscale, whereas the SANS included avolition-anhedonia, asociality, and blocking subscales. Poor premorbid functioning was most strongly associated with poverty of affect and speech. Inappropriate affect and anhedonia-avolition-asociality were moderately correlated with poor response to treatment.

CONCLUSION

Negative symptoms and emotional blunting are similar concepts, but they are not interchangeable. Flatness and inappropriateness appear to be different affective dimensions with different clinical correlations. Inappropriate affect, inattention, and blocking should not be considered negative symptoms.

摘要

背景

在评估精神分裂症患者时,情感迟钝和阴性症状被视为可互换的概念进行研究。

方法

我们对115例连续收治的符合DSM-III-R精神分裂症诊断标准的患者进行了评估。我们对艾布拉姆斯和泰勒情感迟钝量表(SEB)以及安德烈亚森阴性症状评定量表(SANS)进行了主成分分析,并将因子分析得出的分量表与人口统计学和临床变量进行了相关性分析。

结果

两个量表都包含与情感平淡、言语贫乏和情感不适当相对应的分量表。SEB还包括一个冷漠分量表,而SANS包括意志缺乏-快感缺失、社交退缩和思维阻滞分量表。病前功能差与情感平淡和言语贫乏的相关性最强。情感不适当和快感缺失-意志缺乏-社交退缩与治疗反应差呈中度相关。

结论

阴性症状和情感迟钝是相似的概念,但不可互换。情感平淡和情感不适当似乎是不同的情感维度,具有不同的临床相关性。情感不适当、注意力不集中和思维阻滞不应被视为阴性症状。

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