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[典型与非典型支气管成形术治疗支气管源性癌的比较]

[Comparison of typical and atypical bronchoplasty for bronchogenic carcinoma].

作者信息

Ayabe H, Ikari H, Nakamura A, Hayashida K, Itoyanagi N, Tagawa T, Akamine S, Tsuji H, Hara S, Tagawa Y

机构信息

First Department of Surgery, Nagasaki University School of Medicine, Japan.

出版信息

Kyobu Geka. 1993 Mar;46(3):197-201; discussion 202-5.

PMID:8468830
Abstract

One-hundred and twenty-eight patients who underwent bronchoplasty for bronchogenic carcinoma from 1969 to 1990 were retrospectively analyzed. Ninety-six patients had upper sleeve lobectomy or upper lobectomy with wedge bronchoplasty (typical procedure) and 32 underwent bronchoplasty with lobectomy other than upper lobes (atypical bronchoplasty). The two groups were statistically similar in preoperative characteristics including sex, age, cell types and stages. In typical group, right upper sleeve lobectomy was performed in 48 patients, left upper sleeve lobectomy in 27, right upper lobectomy with wedge bronchoplasty in 11, left upper lobectomy with wedge bronchoplasty in 7 and sleeve bronchoplasty alone in 2. In atypical group, right middle and lower lobectomy with sleeve bronchoplasty in 10 patients, left lower sleeve lobectomy in 5, right lower lobectomy with wedge bronchoplasty in 4 and others in 13. Postoperative mortality was 5.2% in the typical group and 9.4% in the atypical group. Postoperative respiratory complications occurred in 16 patients (50%) in the patients with the atypical group and in 33 (34.7%) in those with typical group. Three years and 5 years survival rates in the typical group were 46 and 40% and those in the atypical group, 27 and 18%. However, there was no statistical difference in survival between the two groups. In conclusion, atypical bronchoplasty is useful for preserving the lung parenchyma, but, careful perioperative management and surgical technique of bronchoplasty are mandatory.

摘要

对1969年至1990年间因支气管源性癌接受支气管成形术的128例患者进行回顾性分析。96例患者接受了上叶袖状肺叶切除术或上叶肺叶切除术加楔形支气管成形术(典型手术),32例接受了非上叶肺叶切除术的支气管成形术(非典型支气管成形术)。两组在术前特征(包括性别、年龄、细胞类型和分期)上在统计学上相似。在典型组中,48例行右上叶袖状肺叶切除术,27例行左上叶袖状肺叶切除术,11例行右上叶肺叶切除术加楔形支气管成形术,7例行左上叶肺叶切除术加楔形支气管成形术,2例仅行袖状支气管成形术。在非典型组中,10例行右中、下叶袖状肺叶切除术,5例行左下叶袖状肺叶切除术,4例行右下叶肺叶切除术加楔形支气管成形术,13例为其他情况。典型组术后死亡率为5.2%,非典型组为9.4%。非典型组患者术后呼吸并发症发生率为16例(50%),典型组为33例(34.7%)。典型组3年和5年生存率分别为46%和40%,非典型组分别为27%和18%。然而,两组生存率无统计学差异。总之,非典型支气管成形术有助于保留肺实质,但支气管成形术的围手术期仔细管理和手术技术是必不可少的。

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