Yancey M K, Richards D S
Department of Obstetrics and Gynecology, College of Medicine, University of Florida, Gainesville.
Obstet Gynecol. 1993 May;81(5 ( Pt 2)):847-9.
Unilateral pulmonary agenesis is a rare anomaly that has a relatively frequent association with other congenital malformations. Prognosis depends in part upon associated anomalies and whether the right or left lung is involved. The prenatal sonographic findings of this defect share some similarities with those of other intrathoracic lesions or congenital diaphragmatic hernia.
Our patient had a twin gestation complicated by early discordant growth and hydramnios. The smaller fetus had cardiac dextroposition, abnormally echogenic left lung tissue, and a flattened but clearly visible left hemidiaphragm. No abdominal viscera were seen in the thoracic cavity. Postnatally, this infant was found to have agenesis of the right lung, a tracheoesophageal fistula, and pyloric stenosis.
The diagnosis of unilateral pulmonary agenesis should be considered in a fetus with the sonographic findings of a shift of the mediastinal structures, echogenic lungs, and an intact diaphragm.
单侧肺发育不全是一种罕见的异常情况，常与其他先天性畸形相关。预后部分取决于相关畸形以及受累的是右肺还是左肺。该缺陷的产前超声检查结果与其他胸腔内病变或先天性膈疝的检查结果有一些相似之处。
我们的患者怀有双胎妊娠，并发早期生长不一致和羊水过多。较小的胎儿有心脏右位、左肺组织回声异常增强以及扁平但清晰可见的左半膈。胸腔内未见腹腔脏器。出生后，该婴儿被发现患有右肺发育不全、气管食管瘘和幽门狭窄。
对于超声检查发现纵隔结构移位、肺回声增强且膈肌完整的胎儿，应考虑单侧肺发育不全的诊断。
