Massad L S, Reiss C K, Mutch D G, Haskel E J
Division of Gynecologic Oncology, Washington University School of Medicine, St. Louis, Missouri.
Obstet Gynecol. 1993 May;81(5 ( Pt 2)):886-8.
The potential complications of molar pregnancy are numerous and well defined, but associated peripartum cardiomyopathy has not been reported.
A 16-year-old primigravida with a family history of peripartum cardiomyopathy requiring cardiac transplantation underwent suction curettage of a complete mole at 12 weeks' gestation. Three months after evacuation, she developed congestive heart failure. Radionuclide ventriculography demonstrated an ejection fraction of 30%, echocardiography revealed enlargement and ventricular hypokinesis, and a myocardial biopsy specimen contained hypertrophy and fibrosis without necrosis or active inflammation. The patient improved with medical therapy.
Peripartum cardiomyopathy is a potential complication of molar pregnancy. In spite of the poor prognosis sometimes reported for this disease, good functional outcome may follow.
葡萄胎妊娠的潜在并发症众多且已明确，但与之相关的围产期心肌病尚未见报道。
一名16岁初产妇，有围产期心肌病家族史且曾接受心脏移植，在妊娠12周时行完全性葡萄胎吸刮术。清宫术后3个月，她出现了充血性心力衰竭。放射性核素心室造影显示射血分数为30%，超声心动图显示心脏扩大及心室运动减弱，心肌活检标本显示有心肌肥厚和纤维化，但无坏死或活动性炎症。该患者经药物治疗后病情好转。
围产期心肌病是葡萄胎妊娠的一种潜在并发症。尽管有时报道该病预后不佳，但仍可能获得良好的功能转归。
