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[大鼠白内障的发生作为全身和局部照射后期使其生活质量恶化的因素之一]

[The occurrence of cataract in rats as one of the factors worsening the quality of their lives in the late periods after whole-body and partial irradiation].

作者信息

Vershinina S F, Kabachenko A N, Fedorenko B S

出版信息

Radiobiologiia. 1993 Jan-Feb;33(1):111-5.

PMID:8469731
Abstract

A study was made of the formation of cataract in rats at remote times after whole-body and partial X irradiation. The whole-body radiation loses were 5 and 10 Gy (two fractions of 5 Gy at a 30-day interval). Partial exposure of the head and neck, as well as irradiation of chest were performed with doses of 5, 10 (two fractions at a 30-day interval) and 15 Gy (three 5 Gy fractions at a 30-day interval). It has been shown that cataract develops not only due to the direct effect of radiation on the eye, but also to indirect effect on the experimental animal body (with irradiation of the abdomen and diabetes development).

摘要

对大鼠全身及局部X线照射后远期白内障的形成进行了研究。全身照射剂量为5和10 Gy(30天间隔,分两次给予5 Gy)。头部和颈部的局部照射以及胸部照射的剂量分别为5、10 Gy(30天间隔,分两次给予)和15 Gy(30天间隔,分三次给予,每次5 Gy)。结果表明,白内障的发生不仅是由于辐射对眼睛的直接作用,还与辐射对实验动物机体的间接作用有关(腹部照射及糖尿病的发生)。

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