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[An increase in the radioprotective effect of O-methyltyramine and mezaton by monoamine oxidase inhibitors].

作者信息

Kulinskiĭ V I, Gorkin V Z, Klimova A D, Rumiantseva N P

出版信息

Radiobiologiia. 1993 Jan-Feb;33(1):137-40.

PMID:8469735
Abstract

Specific 2-propynylamine inhibitors of monoamine oxidase (MAO) pargyline and especially chlorgyline, a selective inhibitor of MAO A (but not deprenyl, a selective inhibitor of MAO B) increase the radioprotective effect of small doses of O-methyltyramine and phenylephrine and do not change the efficacy of large doses. This is consistent with the receptor theory of the mechanism of protective action of amines.

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