Abe T, Kusuhara N, Katagiri H, Tomita T, Easton P A
Department of Medicine, School of Medicine, Kitasato University, Kanagawa, Japan.
Respir Physiol. 1993 Mar;91(2-3):183-93. doi: 10.1016/0034-5687(93)90098-u.
In six mongrel dogs under thiopental anesthesia, piezoelectric transducers and bipolar electromyographic (EMG) wires were installed onto left costal, medial crural and lateral crural segments of the diaphragm. During CO2 rebreathing, shortening and EMG activity increased significantly in all three regions of the diaphragm compared to resting breathing. During emesis, (1) both shortening and EMG activity significantly increased compared to resting in costal segment; however, (2) lateral crural shortening was not increased in spite of significant increase in EMG activity; furthermore, (3) the medial crural segment lengthened without any increased EMG activity. These results demonstrate a differential recruitment of costal and crural diaphragm segments, and an additional differential activity within the crural segment between medial and lateral crural regions, during emesis. This activity of the canine diaphragm is consistent with a central influence of emesis upon individual regions of the diaphragm.
在6只硫喷妥钠麻醉的杂种犬中，将压电换能器和双极肌电图（EMG）电极线安装在膈肌的左肋部、小腿内侧和小腿外侧部分。与静息呼吸相比，在二氧化碳重复呼吸期间，膈肌所有三个区域的缩短和肌电图活动均显著增加。在呕吐期间，（1）与静息状态相比，肋部节段的缩短和肌电图活动均显著增加；然而，（2）尽管肌电图活动显著增加，但小腿外侧节段的缩短并未增加；此外，（3）小腿内侧节段延长，而肌电图活动没有任何增加。这些结果表明，在呕吐期间，肋部和小腿部膈肌节段的募集存在差异，并且小腿部节段在小腿内侧和外侧区域之间存在额外的差异活动。犬膈肌的这种活动与呕吐对膈肌各个区域的中枢影响一致。
