Niskanen L, Piirainen M, Koljonen M, Uusitupa M
Department of Clinical Nutrition, University of Kuopio, Finland.
Age Ageing. 1993 Mar;22(2):132-7. doi: 10.1093/ageing/22.2.132.
Energy intake and resting energy expenditure in relation to body composition were studied in female patients with Alzheimer's disease, multi-infarct dementia and in home-living non-demented elderly women. Patients with Alzheimer's disease tended to have lower body weight and higher energy intake (p = NS) than control subjects or patients with multi-infarct dementia. Resting energy expenditure did not differ significantly between the groups (1089 +/- 129 kcal/day for patients with Alzheimer's disease, 1078 +/- 102 kcal/day for patients with multi-infarct dementia and 1188 +/- 143 kcal/day for control women; mean +/- SD). Energy expenditure did not differ between the groups when calculated in relation to body weight or lean body mass. In institutionalized female patients with long-standing Alzheimer's disease the resting energy expenditure was not increased, but they tended to have low body weight despite a high energy intake.
对患有阿尔茨海默病、多发性梗死性痴呆的女性患者以及居家生活的非痴呆老年女性，研究了能量摄入和静息能量消耗与身体组成的关系。与对照组或多发性梗死性痴呆患者相比，阿尔茨海默病患者往往体重较低但能量摄入较高（p = 无显著差异）。各组之间的静息能量消耗无显著差异（阿尔茨海默病患者为1089±129千卡/天，多发性梗死性痴呆患者为1078±102千卡/天，对照女性为1188±143千卡/天；均值±标准差）。按体重或去脂体重计算时，各组之间的能量消耗无差异。在患有长期阿尔茨海默病的住院女性患者中，静息能量消耗并未增加，但尽管能量摄入较高，她们往往体重较低。
