Gevers M, Hack W W, Ree E F, Lafeber H N, Westerhof N
Department of Paediatrics, Free University Hospital, Amsterdam, The Netherlands.
Basic Res Cardiol. 1993 Jan-Feb;88(1):80-5. doi: 10.1007/BF00788533.
Mean arterial pressure (MAP) is the area under the pressure wave form averaged over the cardiac cycle. A widely used rule of thumb to estimate MAP of peripheral arterial pressure waves in adults is adding one-third of the pulse pressure (PP) to diastolic arterial pressure (DAP). However, radial artery pressure waves in newborns differ from those in adults and resemble proximal aortic pressure waves, so that the above-mentioned calculation of MAP may not be correct. The present study was set up to obtain an arithmetical approximation to derive MAP from blood pressure waves measured in the radial artery of the neonate. We accurately recorded about 300 invasively obtained blood pressure curves in the radial artery of 10 neonates admitted for intensive care. We found that MAP in the radial artery in these neonates can be well approximated by adding 46.6% PP to DAP (range 43.0-50.1%). We suggest that the rule of thumb to derive MAP from radial artery waves in the neonate to be approximately the average of systolic and diastolic pressure, as opposed to adding one-third of the pulse pressure to the diastolic value in the adult.
平均动脉压（MAP）是心动周期中压力波形下的面积平均值。一种广泛用于估算成体外周动脉压力波MAP的经验法则是，将脉压（PP）的三分之一加到舒张期动脉压（DAP）上。然而，新生儿的桡动脉压力波与成人不同，类似于近端主动脉压力波，因此上述MAP的计算可能不正确。本研究旨在获得一种算术近似值，以便从新生儿桡动脉测量的血压波中推导MAP。我们准确记录了10名因重症监护入院的新生儿桡动脉中约300条通过侵入性获得的血压曲线。我们发现，这些新生儿桡动脉中的MAP可以通过将46.6%的PP加到DAP上得到很好的近似（范围为43.0 - 50.1%）。我们建议，从新生儿桡动脉波推导MAP的经验法则应近似于收缩压和舒张压的平均值，而不是像成人那样将脉压的三分之一加到舒张期值上。
