Morris J, Goddard M
Centre for Health Economics, University of York, Heslington, U.K.
Eur J Cancer. 1993;29A(5):766-70. doi: 10.1016/s0959-8049(05)80364-8.
Arguments are being made more frequently to incorporate economic evaluations and quality of life assessments into clinical trials. Using a randomised, multicentre, phase 3 cancer clinical trial as an example, this paper outlines the importance of including such assessments; the practical considerations associated with the design of such trials; the methods for collecting such data; and, how such data can be used. Finally, it is emphasised that the anticipated benefits of collecting data relating to resource use and quality of life should outweigh the associated costs to research funding organisations.
越来越多的人主张将经济评估和生活质量评估纳入临床试验。本文以一项随机、多中心、3期癌症临床试验为例，概述了纳入此类评估的重要性；与此类试验设计相关的实际考虑因素；收集此类数据的方法；以及此类数据的使用方式。最后强调，收集与资源使用和生活质量相关数据的预期收益应超过研究资助机构的相关成本。
