Murphy D F, Medley C
Department of Anaesthesia, Sir Charles Gairdner Hospital, Nedlands, Western Australia.
Br J Anaesth. 1993 Mar;70(3):298-300. doi: 10.1093/bja/70.3.298.
Indomethacin commenced before operation was compared with postoperative indomethacin administration for pain relief in patients after elective thoracic surgery. In addition to indomethacin, all patients received i.v. opioids titrated to their individual requirements. There was no significant difference between the two groups in quality of pain relief, in cumulative opioid requirement or in the incidence of adverse effects. The quality of pain relief compared well with previous similar studies using this technique.
将术前开始使用吲哚美辛与术后使用吲哚美辛用于择期胸外科手术后患者的疼痛缓解进行了比较。除吲哚美辛外，所有患者均接受静脉注射阿片类药物，并根据个体需求进行滴定。两组在疼痛缓解质量、累积阿片类药物需求量或不良反应发生率方面无显著差异。与以往使用该技术的类似研究相比，疼痛缓解质量良好。
