Monteiro L, Almeida-Pinto J, Rocha N, Lopes G, Rocha J
Department of Neurology, Hospital Geral de Santo António, Oporto, Portugal.
Br J Radiol. 1993 Mar;66(783):271-2. doi: 10.1259/0007-1285-66-783-271.
Acute encephalopathy is a recognized toxic effect of Cyclosporin A (CsA) in organ transplantation recipients. A 16-year-old girl presented with acute encephalopathy 2 weeks after CsA and methylprednisolone medication for idiopathic uveitis. Magnetic resonance imaging showed cortical and white matter occipital changes, which were not visible 2 months later. With expanding indication for CsA use, an increasing number of neurotoxic cases are to be expected.
急性脑病是环孢素A（CsA）在器官移植受者中公认的毒性作用。一名16岁女孩在使用CsA和甲基泼尼松龙治疗特发性葡萄膜炎2周后出现急性脑病。磁共振成像显示枕叶皮质和白质有改变，2个月后这些改变消失。随着CsA使用指征的扩大，预计会出现越来越多的神经毒性病例。
