Sim F H, Edmonson J H, Wold L E
Department of Orthopedics, Mayo Clinic, Rochester, MN 55905.
Clin Orthop Relat Res. 1993 Apr(289):106-12.
Although the previous outlook for patients with soft-tissue tumors was poor, in recent years advances have been made in earlier recognition and management of soft-tissue sarcomas. Advances include improved clinical pathologic correlation and clinical staging, as well as improved concept of what constitutes adequate surgical management. In addition, recent advances in surgical adjuvant treatment programs promise better results. Moreover, a better understanding of the biology of cancer and the development of sophisticated techniques of molecular biology should lead to more effective treatment.
尽管过去软组织肿瘤患者的预后较差,但近年来在软组织肉瘤的早期识别和管理方面取得了进展。进展包括改善临床病理相关性和临床分期,以及对充分手术管理的构成有了更好的概念。此外,手术辅助治疗方案的最新进展有望带来更好的结果。而且,对癌症生物学的更好理解和分子生物学复杂技术的发展应该会带来更有效的治疗。