Sadat-Ali M
Department of Orthopaedic Surgery, College of Medicine and Medical Sciences, King Faisal University, Dammam, Saudi Arabia.
Clin Orthop Relat Res. 1993 May(290):200-5.
Avascular necrosis of the femoral head (ANFH) is one of the crippling complications of sickle cell disease (SCD), and to date there is no classification that could identify patients in the early phase of the necrosis. Based on the experience of 66 ANFH in 43 patients with SC hemoglobinopathy, the necrosed hips were classified into four grades, Grade I to Grave IV, based on patient history, clinical evaluation, and radiologic examination. In Grade I, the patient complains of the mildest symptoms with minimal clinical signs and radiologic changes. The most severe form, Grade IV, is where the findings are unbearable pain with disability and marked roentgenographic evidence of osteonecrosis. This classification identifies patients in Grade I and II, which, with early diagnosis and proper management, could delay further deterioration of the necrosed femoral head.
股骨头缺血性坏死（ANFH）是镰状细胞病（SCD）致残性并发症之一，迄今为止，尚无能够识别坏死早期患者的分类方法。基于43例镰状细胞血红蛋白病患者中66例ANFH的经验，根据患者病史、临床评估和影像学检查，将坏死髋关节分为四个等级，即I级至IV级（重度）。在I级中，患者症状最轻，临床体征和影像学改变最少。最严重的形式是IV级，其表现为难以忍受的疼痛、残疾以及明显的骨坏死X线证据。这种分类可识别I级和II级患者，通过早期诊断和适当治疗，可延缓坏死股骨头的进一步恶化。
