Rossi M, Zanardi M
Divisione Neurologica, USL 11, Ospedali Civili Sampierdarena Genova.
Clin Ter. 1993 Feb;142(2):141-4.
In this study we evaluated the safety/efficacy of citicoline in 30 patients affected by atherosclerotic processes with cerebral localization. Aim of this study was to confirm, from a clinical point of view, the efficacy of citicoline in increasing blood flow in the vascular zone and in exerting a trophic action on cerebral cells improving the symptoms related to the chronic cerebrovasculopathy. Therapeutic effect was evaluated, by means of subjective parameters, at the beginning, during and at the end of the study. The results obtained was statistically analyzed confirming the efficacy of citicoline on the subjective symptomatology. Safety was excellent in all cases.
在本研究中，我们评估了胞磷胆碱对30例患有脑局部动脉粥样硬化病变患者的安全性/疗效。本研究的目的是从临床角度证实胞磷胆碱在增加血管区域血流量以及对脑细胞发挥营养作用以改善与慢性脑血管病相关症状方面的疗效。在研究开始、进行期间及结束时，通过主观参数评估治疗效果。对所得结果进行统计学分析，证实了胞磷胆碱对主观症状的疗效。在所有病例中安全性均极佳。
