Arranz J, Ganoza C
Arzneimittelforschung. 1983;33(7A):1071-3.
Ten patients older than 60 years suffering from tardive dyskinesia consecutive to a long-term treatment with neuroleptics were included in a study with the scope to check the efficacy of cytidine diphosphate choline (CDP-choline, citicoline, Somazina) in these disorders. The drug was administered for four weeks at daily doses of 500-1200 mg. The evaluations of the symptomatology carried out with the Simpson's abbreviated scale, showed statistically significant reductions between the beginning and the end of the treatment. The tolerance of the drug was satisfactory.
10名年龄超过60岁、因长期使用抗精神病药物而患有迟发性运动障碍的患者被纳入一项研究，该研究旨在检验胞二磷胆碱（CDP-胆碱、西替考林、索马西纳）对这些疾病的疗效。该药物以每日500 - 1200毫克的剂量给药四周。使用辛普森简易量表对症状进行评估，结果显示治疗开始和结束之间有统计学意义的症状减轻。该药物的耐受性良好。
