Stenström U, Wikby A, Hörnquist J O, Andersson P O
University College of Health Sciences, Eksjö, Sweden.
Gen Hosp Psychiatry. 1993 Mar;15(2):82-8. doi: 10.1016/0163-8343(93)90101-s.
Sixty-six outpatients with insulin-dependent diabetes mellitus (IDDM) filled in a life event questionnaire reflecting positive and negative life events perceived to have occurred over the past year. The difference in glycosylated hemoglobin (HbA1C) measures obtained before and after the 1-year period in question (Delta-HbA1C) served as a proxy measure of change in metabolic control. Among males, those reporting predominantly negative life events showed poorer metabolic control than those reporting few negative life events or none. Among females, the greater the number of events reported, especially positive ones, the greater the change for the better in HbA1C over the event year studied. These results suggest that life events may be significant to metabolic control in insulin-dependent diabetes. This only becomes apparent, however, when the two genders are analyzed separately, as various relationships found in one sex may be lacking or even opposite to the other sex. The findings also suggest the importance to the diabetic of learning of life events both the relative lack and preponderance of positive as well as negative events.
66名胰岛素依赖型糖尿病（IDDM）门诊患者填写了一份生活事件问卷，该问卷反映了过去一年中所感知到的积极和消极生活事件。在所述的1年期间之前和之后获得的糖化血红蛋白（HbA1C）测量值的差异（Δ-HbA1C）用作代谢控制变化的替代指标。在男性中，那些主要报告消极生活事件的人比那些报告很少或没有消极生活事件的人代谢控制更差。在女性中，报告的事件数量越多，尤其是积极事件，在研究的事件年度中HbA1C改善的变化就越大。这些结果表明，生活事件可能对胰岛素依赖型糖尿病的代谢控制具有重要意义。然而，只有当对两性分别进行分析时，这一点才会变得明显，因为在一种性别中发现的各种关系在另一种性别中可能不存在甚至相反。研究结果还表明，了解生活事件（包括积极事件和消极事件的相对缺乏和优势）对糖尿病患者很重要。
