双侧睾丸切除术在D-2期前列腺癌治疗中的应用
Bilateral orchiectomy in the management of stage D-2 prostate cancer.
作者信息
Guinan P, Firfer R, Targonski P, Rubenstein M
机构信息
Division of Urology, University of Illinois, Chicago.
出版信息
Int Surg. 1993 Jan-Mar;78(1):73-5.
The records of 115 patients with stage D-2 prostate cancer treated with bilateral orchiectomy were reviewed to determine the effect of this procedure in previously untreated patients and in patients who had prior hormone therapy. Previously untreated patients survived 22.8 months while those who had prior hormone therapy survived 39.3 months (p < 0.001). Bilateral orchiectomy may be of additional clinical benefit in patients with advanced prostate cancer who have had prior hormone therapy.
回顾了115例接受双侧睾丸切除术治疗的D-2期前列腺癌患者的记录，以确定该手术对既往未接受治疗的患者以及既往接受过激素治疗的患者的效果。既往未接受治疗的患者存活22.8个月，而既往接受过激素治疗的患者存活39.3个月（p<0.001）。对于既往接受过激素治疗的晚期前列腺癌患者，双侧睾丸切除术可能具有额外的临床益处。
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