儿童螨虫性哮喘：一项关于接触屋尘螨与疾病活动之间关系的研究。
Mite asthma in childhood: a study of the relationship between exposure to house dust mites and disease activity.
作者信息
Kivity S, Solomon A, Soferman R, Schwarz Y, Mumcuoglu K Y, Topilsky M
机构信息
Allergy Unit, Ichilov Hospital, Tel-Aviv Sourasky Medical Center, Israel.
出版信息
J Allergy Clin Immunol. 1993 Apr;91(4):844-9. doi: 10.1016/0091-6749(93)90341-c.
BACKGROUND
Children with asthma are commonly sensitized to the house dust mite.
METHODS
We took monthly measurements from July to December of the amount of mites in the mattresses of asthmatic children and correlated them with symptom score, pulmonary function, and airway hyperreactivity to methacholine.
RESULTS
In spite of the high number of Dermatophagoides pteronyssinus throughout this period, symptom and treatment scores, as well as PC20 to methacholine, worsened during the months of September and October.
CONCLUSIONS
It is concluded that when asthmatic children allergic to mites are exposed to high levels of mite allergen, the number of mites in the mattress dust no longer correlate with increased symptoms, and that other factors are more likely to be associated with exacerbation.
背景
哮喘儿童通常对屋尘螨敏感。
方法
我们在7月至12月每月测量哮喘儿童床垫中的螨虫数量，并将其与症状评分、肺功能以及对乙酰甲胆碱的气道高反应性相关联。
结果
尽管在此期间嗜热栖尘螨数量众多，但在9月和10月，症状和治疗评分以及对乙酰甲胆碱的PC20均恶化。
结论
得出的结论是，当对螨虫过敏的哮喘儿童暴露于高水平的螨虫过敏原时，床垫灰尘中的螨虫数量不再与症状增加相关，其他因素更可能与病情加重有关。
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