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双瓣膜置换术后人工瓣膜心内膜炎

[Prosthetic valve endocarditis after double valve replacement].

作者信息

Yamaguchi A, Kitamura N, Kawashima M, Miki T, Tamura H

机构信息

Department of Cardiovascular Surgery, Osaka National Hospital, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1993 Feb;41(2):282-7.

PMID:8473797
Abstract

This is a report of a patient who underwent re-AVR due to prosthetic valve endocarditis after double valve replacement (MVR, AVR). A 54-year-old female was admitted to other hospital on April 14, 1990, because of high fever, progressive anemia, and cardiomegaly. The patient was hospitalized to our department urgently with the diagnosis of prosthetic valve endocarditis. Arterial blood culture grew methicillin-resistant Staphylococcus epidermidis. Echocardiography showed a vegetation at the disc of the mechanical valve in the mitral position, but we could not find any vegetation or thrombus there at the reoperation, and the aortic mechanical valve seemed to be intact. Signs of inflammation continued to be positive after reoperation. On the 33rd hospital day, a diastolic murmur was heard, and emergency cardiac catheterization was done. Detachment of the prosthetic aortic valve and rupture of the sinus of Valsalva due to mycotic aneurysm, and the dissection of the aorta had occurred. We performed re-AVR and replacement of the ascending aorta. The patient died of multiple organ failure following drug-induced hepatic failure. It is suggestive that we missed the prosthetic aortic valve endocarditis during the reoperation. Our thoughts and introspections on the echocardiographic diagnosis of the prosthetic valve endocarditis after double valve replacement were discussed.

摘要

这是一份关于一名在双瓣置换术(二尖瓣置换术、主动脉瓣置换术)后因人工瓣膜心内膜炎接受再次主动脉瓣置换术患者的报告。一名54岁女性于1990年4月14日因高热、进行性贫血和心脏扩大入住其他医院。该患者因人工瓣膜心内膜炎的诊断紧急入住我院。动脉血培养出耐甲氧西林表皮葡萄球菌。超声心动图显示二尖瓣位机械瓣膜瓣盘处有赘生物,但再次手术时我们在该处未发现任何赘生物或血栓,主动脉机械瓣膜似乎完好无损。再次手术后炎症迹象仍为阳性。住院第33天,听到舒张期杂音,遂进行急诊心导管检查。发现人工主动脉瓣脱离,因霉菌性动脉瘤导致主动脉窦破裂,且发生了主动脉夹层。我们进行了再次主动脉瓣置换术及升主动脉置换术。患者因药物性肝衰竭继发多器官衰竭死亡。提示我们在再次手术时漏诊了人工主动脉瓣心内膜炎。讨论了我们对双瓣置换术后人工瓣膜心内膜炎超声心动图诊断的思考与反思。

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