Markusse H M, van Putten W I, Breedveld F C, Oudkerk M
Department of Rheumatology, Dr. Daniel den Hoed Clinic, Rotterdam, The Netherlands.
J Rheumatol. 1993 Feb;20(2):279-83.
Digital subtraction sialography of the parotid glands was performed in 34 patients with primary Sjögren's syndrome (SS) and 78 patients suspected of having primary SS in whom the diagnosis could be excluded (NON-SS). The following sialographic features were found more frequently in the patients with primary SS than in the NON-SS patients: a sparse overall branching pattern of the ducts, progressive widening and irregularity of the duct walls, disappearance of a homogeneous parenchyma blush and the occurrence of peripheral acinar dilations. The most discriminating findings between the 2 patient groups were the presence of acinar dilations and the disappearance of the homogeneous parenchyma blush. The sensitivity and specificity of the presence of acinar dilatations were 79 and 95%, respectively. Both the sensitivity and specificity of the presence of an irregular or absent parenchyma blush were 91%. The concurrent finding of acinar dilatations and an irregular or absent parenchyma blush had a sensitivity of 77% and a specificity of 95%. We conclude that digital subtraction sialography is a useful adjunctive diagnostic procedure for primary SS.
对34例原发性干燥综合征（SS）患者以及78例疑似原发性SS但最终排除诊断的患者（非SS）进行了腮腺数字减影涎管造影。以下涎管造影特征在原发性SS患者中比在非SS患者中更常见：导管整体分支模式稀疏、导管壁逐渐增宽和不规则、均匀的实质充盈消失以及周边腺泡扩张。两组患者之间最具鉴别性的表现是腺泡扩张的存在和均匀实质充盈的消失。腺泡扩张存在的敏感性和特异性分别为79%和95%。实质充盈不规则或缺失的敏感性和特异性均为91%。腺泡扩张与实质充盈不规则或缺失同时出现时，敏感性为77%，特异性为95%。我们得出结论，数字减影涎管造影是原发性SS的一种有用的辅助诊断方法。
