Adamek R J, Wegener M, Wedmann B, Büttner T, Ricken D
Medizinische Klinik, Ruhr-Universität, St.-Josef-Hospital, Bochum.
Leber Magen Darm. 1993 Mar;23(2):91-3.
Central nervous system vasculitis in Crohn's disease. A 36-years old man was referred to the hospital because of severe headache, vertigo and right sided combined motor-sensory hemiparesis. There was a history of Crohn's disease with an acute exacerbation only two months ago. Magnetic resonance imaging detected a vascular lesion of the left brainstem and serologic investigations revealed circulating immunocomplexes and p-antineutrophil cytoplasmic autoantibodies (p-ANCA). Further investigations care no evidence of arteriosclerotic cerebrovascular disease. These findings therefore suggest that cerebral vasculitis secondary to Crohn's disease was the underlying cause of this focal neurologic deficit.
克罗恩病相关的中枢神经系统血管炎。一名36岁男性因严重头痛、眩晕及右侧运动感觉混合性偏瘫被转诊至医院。该患者有克罗恩病病史,仅在两个月前有急性加重。磁共振成像检测到左脑干有血管病变,血清学检查发现循环免疫复合物及抗中性粒细胞胞浆抗体(p-ANCA)。进一步检查未发现动脉硬化性脑血管病的证据。因此,这些发现提示克罗恩病继发的脑血管炎是该局灶性神经功能缺损的潜在病因。