Much T, Wüthrich B
Schweiz Med Wochenschr. 1977 Feb 26;107(8):267-71.
100 thrombocytopenia tests (TT) from 73 patients with suspected food allergies were critically examined to establish the value of this method compared with case history, skin tests and, where possible, with the RAST for determination of specific IgE antibodies. 85% of the tests most probably, or definitely, provided the correct result. 10% of the results were either false positives or false negatives, and 5% were inconclusive. A flare-up was observed after 18% of the tests. No positive TT for milk, as the most frequent allergen, was observed in a control group of 20 healthy persons. The thrombocytopenia test is a useful exposure test but should be regarded as a supplement to skin tests and other methods of allergy diagnosis.
对73例疑似食物过敏患者进行了100次血小板减少试验(TT),并与病史、皮肤试验以及在可能的情况下与用于测定特异性IgE抗体的RAST进行了严格比较,以确定该方法的价值。85%的试验很可能或肯定提供了正确结果。10%的结果为假阳性或假阴性,5%的结果不确定。18%的试验后观察到病情加重。在20名健康人的对照组中,未观察到作为最常见过敏原的牛奶的阳性TT结果。血小板减少试验是一种有用的暴露试验,但应被视为皮肤试验和其他过敏诊断方法的补充。