Goldschmidt G, Olsen E, Svane O
Danish Energy Agency, København.
Pharmacol Toxicol. 1993;72 Suppl 1:139-43. doi: 10.1111/j.1600-0773.1993.tb01681.x.
The ultimate solution in prevention of occupational cancer risks would be to remove carcinogens from the working environment. Elimination of carcinogenic substances can be achieved by replacement of the carcinogen with non-carcinogen(s) having the same functionality, or by using a different process that produces adequate results without the use of carcinogenic agents. This paper presents selected methods and tools, which have been used for substitution purposes in practice. These are: 1. a strategy for substitution, 2. a tool for creating ideas on how to substitute, 3. a software package, SUBTEC, for solving some technical and industrial hygiene problems, and 4. a proposal for a strategy to deal with organizational and psychological barriers encountered when changes are to be introduced.
预防职业癌症风险的最终解决方案是从工作环境中去除致癌物。通过用具有相同功能的非致癌物替代致癌物，或采用不使用致癌剂就能产生足够效果的不同工艺，可以实现致癌物质的消除。本文介绍了一些在实践中用于替代目的的方法和工具。它们是：1. 替代策略；2. 用于产生替代想法的工具；3. 用于解决一些技术和工业卫生问题的软件包SUBTEC；4. 一项应对引入变革时遇到的组织和心理障碍的策略建议。
