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脑脓肿的立体定向抽吸:这是首选治疗方法吗?

Stereotactic aspiration of brain abscesses: is this the treatment of choice?

作者信息

Stapleton S R, Bell B A, Uttley D

机构信息

Department of Neurosurgery, Atkinson Morley's Hospital, Wimbledon, London, U.K.

出版信息

Acta Neurochir (Wien). 1993;121(1-2):15-9. doi: 10.1007/BF01405177.

Abstract

Despite a reduction in the mortality of patients with brain abscess since the introduction of the computed tomography (CT) scanner, controversy persists as to the preferred method of treatment for this condition. Eleven patients were treated by CT guided stereotactic aspiration of pus and appropriate antibiotic therapy. A total of 14 aspirations were performed. Ten abscesses were supratentorial and one was in the posterior fossa. In 9 patients a bacterial cause was identified while in 2 a fungus was identified. A good outcome was achieved in 7 patients but 3 patients died. Another elderly patient remains disabled at home. The deaths occurred in severely systemically ill patients with poor conscious levels on admission. Only one patient has epilepsy, controlled with anticonvulsants while another has not had further seizures since abscess treatment a year ago. Stereotactic aspiration should be considered the treatment of choice in all but the most superficial and largest cerebral abscesses, although the mortality of this condition in the severely ill remains high.

摘要

自从计算机断层扫描(CT)扫描仪问世以来,尽管脑脓肿患者的死亡率有所降低,但对于这种疾病的首选治疗方法仍存在争议。11例患者接受了CT引导下的立体定向脓肿抽吸术及适当的抗生素治疗。总共进行了14次抽吸。10个脓肿位于幕上,1个位于后颅窝。9例患者确定了细菌病因,2例确定了真菌病因。7例患者预后良好,但3例患者死亡。另一名老年患者在家中仍有残疾。死亡发生在入院时意识水平差的严重全身性疾病患者中。只有1例患者患有癫痫,通过抗惊厥药得到控制,而另1例自一年前脓肿治疗后未再发作。除了最表浅和最大的脑脓肿外,立体定向抽吸术应被视为所有脑脓肿的首选治疗方法,尽管重症患者的死亡率仍然很高。

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