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采用计算机断层扫描引导下立体定向抽吸术治疗脑干脓肿。

Brain stem abscess managed with computed tomography-guided stereotactic aspiration.

作者信息

Nauta H J, Contreras F L, Weiner R L, Crofford M J

出版信息

Neurosurgery. 1987 Mar;20(3):476-80. doi: 10.1227/00006123-198703000-00022.

Abstract

The importance of stereotactic aspiration to the successful management of three cases of brain stem abscess is discussed with special reference to the advantages offered over medical treatment alone. Stereotactic aspiration allows evacuation of pus, accurate bacteriological diagnosis, selection of an optimal antibiotic regimen, and instillation of antibiotics directly into the abscess cavity. In two of the three cases described here, the abscess reaccumulated after initial aspiration despite appropriate maximal medical therapy. A repeat aspiration was required before resolution occurred. We conclude that medical management alone is not adequate for some cases of brain stem abscess. There was no morbidity that could be attributed to the procedure, suggesting that the risk of stereotactic aspiration is probably quite low and is likely to be less than the risk of incorrect diagnosis, suboptimal choice of antibiotics, or progression of the lesion despite appropriate maximal medical therapy.

摘要

本文讨论了立体定向穿刺抽吸术对三例脑干脓肿成功治疗的重要性,并特别提及了相较于单纯药物治疗的优势。立体定向穿刺抽吸术可排出脓液、进行准确的细菌学诊断、选择最佳抗生素治疗方案,并将抗生素直接注入脓肿腔。在本文描述的三例病例中,有两例尽管进行了适当的最大剂量药物治疗,但在初次抽吸后脓肿仍复发。在脓肿消退之前需要再次抽吸。我们得出结论,对于某些脑干脓肿病例,单纯药物治疗是不够的。该操作未导致任何可归因的并发症,这表明立体定向穿刺抽吸术的风险可能相当低,且可能低于错误诊断、抗生素选择不当或尽管进行了适当的最大剂量药物治疗但病变仍进展的风险。

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