Pattinson R C, Hope P, Imhoff R, Manning N, Mannion V, Redman C W
Nuffield Department of Obstetrics and Gynecology, John Radcliffe Hospital, Oxford, United Kingdom.
Am J Perinatol. 1993 Mar;10(2):135-8. doi: 10.1055/s-2007-994645.
Absence of end-diastolic velocities (AEDV) is the most severe waveform abnormality detected by Doppler ultrasound examination of the umbilical artery. It is associated with fetal hypoxemia and acidemia. If AEDV predisposed to more neonatal complications, then it might be an indication for earlier delivery. This was investigated in 21 preterm fetuses with AEDV who were matched for gestational age at delivery with 21 with end-diastolic velocities. All fetuses were delivered electively before 36 weeks' gestation of mothers who were hypertensive. The fetal heart rate (FHR) variability, birthweight, and umbilical arterial blood pH were significantly lower in the AEDV group. However, the neonatal outcomes were similar except for less severe hyaline membrane disease and lower initial platelet counts in the AEDV group. At present, fetuses with umbilical arterial AEDV need not be delivered earlier than indicated by the FHR pattern, nor should neonatal management be altered on the basis of antenatal AEDV.
舒张末期血流速度缺失（AEDV）是通过脐动脉多普勒超声检查检测到的最严重的波形异常。它与胎儿低氧血症和酸血症有关。如果AEDV易导致更多新生儿并发症，那么它可能是提前分娩的一个指征。对21例有AEDV的早产胎儿进行了研究，这些胎儿在分娩时的胎龄与21例有舒张末期血流速度的胎儿相匹配。所有胎儿均在母亲妊娠36周前择期分娩，母亲患有高血压。AEDV组的胎儿心率（FHR）变异性、出生体重和脐动脉血pH值显著较低。然而，除了AEDV组的透明膜病较轻和初始血小板计数较低外，两组的新生儿结局相似。目前，有脐动脉AEDV的胎儿不必比FHR模式所指示的时间更早分娩，也不应根据产前AEDV改变新生儿管理。
