Smith P, Rice M, Ricci N, Toogood I, Roberton D
Department of Paediatrics and Oncology, Adelaide Medical Centre for Women and Children, South Australia.
Acta Paediatr. 1993 Feb;82(2):217-9. doi: 10.1111/j.1651-2227.1993.tb12645.x.
Paraneoplastic syndromes are rare in paediatric oncology. This report describes a four-year-old Cantonese child whose sole presenting symptom was acrocyanosis who was found to have Burkitt's lymphoma in association with the presence of positive antinuclear antibodies, antineutrophil cytoplasmic antibodies, antiendothelial antibodies and elevated serum immunoglobulin G concentrations. Digital ischaemia has not been described as a presenting symptom of Burkitt's lymphoma, although this association has been reported in 25 patients with other malignancies.
副肿瘤综合征在儿童肿瘤学中较为罕见。本报告描述了一名4岁的粤语儿童,其唯一的首发症状是手足发绀,该患儿被发现患有伯基特淋巴瘤,同时存在抗核抗体、抗中性粒细胞胞浆抗体、抗内皮细胞抗体阳性以及血清免疫球蛋白G浓度升高。虽然在25例患有其他恶性肿瘤的患者中曾报道过这种关联,但数字缺血尚未被描述为伯基特淋巴瘤的首发症状。