Asano T, Murayama T, Hirai Y, Shoji J
School of Pharmaceutical Sciences, Showa University, Tokyo, Japan.
Chem Pharm Bull (Tokyo). 1993 Mar;41(3):566-70. doi: 10.1248/cpb.41.566.
Two monoterpene glycosides, tentatively named OJV-I (1) and OJV-II (2), and eight steroidal glycosides, tentatively named OJV-III (3), OJV-IV (4), OJV-V (5), OJV-VI (6), OJV-VII (7), OJV-VIII (8), OJV-IX (9) and OJV-X (10), were isolated from the butanol-soluble fraction of the fresh subterranean part of Ophiopogon japonicus KER-GAWLER cv. Nanus. Among these compounds, 1, 2, 3, 4, 5, 6 and 7 were identified as l-borneo1 O-beta-D-glucopyranoside, l-borneo1 O-beta-D-apiofuranosyl (1-->6)-beta-D-glucopyranoside, ophiopogonin B, glycoside C, ophiopogonin D, Ls-10, and ruscogenin 1-O-sulfate, respectively. The structures of compounds 8, 9, and 10 were established to be (23S,24S,25S)-23,24-dihydroxyruscogenin 1-O-[ alpha-L-rhamnopyranosyl(1-->2)] [beta-D-xylopyranosyl(1-->3)]-alpha-L-arabinopyranoside 24-O-beta-D-fucopyranoside, (23S,24S,25S)-23,24-dihydroxyruscogenin I-O-[alpha-L-2,3,4-tri-O-acetylrhamnopyranosyl(1-->2)][beta-D-xylo pyranosyl(1-->3)]-alpha-L-arabinopyranoside 24-O-beta-D-fucopyranoside, and (23S,24S,25S)-23,24-dihydroxyruscogenin 1-O-[alpha-L-2,3,4-tri-O-acetylrhamnopyranosyl(1-->2)] [beta-D-xylopyranosyl(1-->3)]=alpha-L-arabinopyranoside 24-O-beta-D-fucopyranoside, respectively.
从矮麦冬新鲜地下部分的丁醇可溶部分中分离出两种单萜糖苷，暂命名为OJV-I（1）和OJV-II（2），以及八种甾体糖苷，暂命名为OJV-III（3）、OJV-IV（4）、OJV-V（5）、OJV-VI（6）、OJV-VII（7）、OJV-VIII（8）、OJV-IX（9）和OJV-X（10）。在这些化合物中，1、2、3、4、5、6和7分别被鉴定为l-龙脑1-O-β-D-吡喃葡萄糖苷、l-龙脑1-O-β-D-阿洛呋喃糖基（1→6）-β-D-吡喃葡萄糖苷、麦冬皂苷B、糖苷C、麦冬皂苷D、Ls-10和鲁斯可皂苷元1-O-硫酸盐。化合物8、9和10的结构分别确定为（23S，24S，25S）-23,24-二羟基鲁斯可皂苷元1-O-[α-L-鼠李吡喃糖基（1→2）][β-D-木吡喃糖基（1→3）]-α-L-阿拉伯吡喃糖苷24-O-β-D-岩藻吡喃糖苷、（23S，24S，25S）-23,24-二羟基鲁斯可皂苷元I-O-[α-L-2,3,4-三-O-乙酰基鼠李吡喃糖基（1→2）][β-D-木吡喃糖基（1→3）]-α-L-阿拉伯吡喃糖苷24-O-β-D-岩藻吡喃糖苷，以及（23S，24S，25S）-23,24-二羟基鲁斯可皂苷元1-O-[α-L-2,3,4-三-O-乙酰基鼠李吡喃糖基（1→2）][β-D-木吡喃糖基（1→3）]=α-L-阿拉伯吡喃糖苷24-O-β-D-岩藻吡喃糖苷。
