Roenigk R K, Brodland D G
Department of Dermatology, Mayo Clinic, Rochester, Minnesota.
Dermatol Clin. 1993 Apr;11(2):349-59.
Facial chemical peel encompasses a plethora of procedures or techniques and so may be confusing. This should not blunt one's enthusiasm for what chemexfoliation can achieve. With the use of TCA, chemical peel is a safe, effective, elegant, and simple method for treating some common problems of photoaged, fair skin (Table 7). When a standardized technique is used, it is possible to quantify the therapeutic effects and to predict the outcome reliably. Variations of chemical peel will be used as clinicians try to achieve better results. If possible, variations from standard techniques should be scientifically studied and quantified to establish their safety and efficacy. The goal of chemical face peeling is not simply to achieve a deep or longer-lasting peel. The highest concentrations of TCA and phenol may cause full-thickness facial chemical burns and leave long-lasting scars. Therefore, variations on standard techniques provide only subjective, difficult-to-measure benefits. Conversely, standardized testing on the facial skin of patients is difficult and thus we chose an animal model. Clinicians, especially dermatologists, who want to perform chemical peel should know the indications. Using the procedures described here and in other articles, one can safely and reliably undertake facial chemical peel.
面部化学剥脱术包含众多程序或技术，因此可能会让人感到困惑。但这不应削弱人们对化学剥脱所能取得效果的热情。使用三氯乙酸（TCA）时，化学剥脱术是一种安全、有效、美观且简单的方法，可用于治疗一些光老化白皙皮肤的常见问题（表7）。采用标准化技术时，能够量化治疗效果并可靠地预测结果。随着临床医生试图取得更好的效果，化学剥脱术会有不同的变化形式。如果可能，应科学研究并量化与标准技术的差异，以确定其安全性和有效性。面部化学剥脱的目标并非仅仅是实现深度或持久的剥脱。TCA和苯酚的最高浓度可能会导致全层面部化学烧伤并留下持久的疤痕。因此，标准技术的变化形式仅提供主观的、难以衡量的益处。相反，在患者面部皮肤进行标准化测试很困难，所以我们选择了动物模型。想要进行化学剥脱的临床医生，尤其是皮肤科医生，应该了解其适应证。使用本文及其他文章中描述 的程序，就可以安全可靠地进行面部化学剥脱。
