RP 59500，一种对北美葡萄球菌近期分离株具有高度活性的新型链阳性菌素。
RP 59500, a new streptogramin highly active against recent isolates of North American staphylococci.
作者信息
Archer G L, Auger P, Doern G V, Ferraro M J, Fuchs P C, Jorgensen J H, Low D E, Murray P R, Reller L B, Stratton C W
机构信息
Medical College of Virginia, Richmond.
出版信息
Diagn Microbiol Infect Dis. 1993 Mar-Apr;16(3):223-6. doi: 10.1016/0732-8893(93)90113-l.
To assess the potential clinical utility of RP 59500, 10 investigators from separate locations in the United States and Canada each tested approximately 200 current isolates of staphylococci (Staphylococcus aureus and coagulase-negative staphylococci) by a standard protocol. RP 59500 was highly active (MIC90 < or = 2 micrograms/ml) against all strains, including those that were resistant to oxacillin, ciprofloxacin, erythromycin, and spiramycin.
为评估RP 59500的潜在临床效用，来自美国和加拿大不同地点的10名研究人员各自按照标准方案对约200株当前的葡萄球菌分离株（金黄色葡萄球菌和凝固酶阴性葡萄球菌）进行了检测。RP 59500对所有菌株均具有高活性（MIC90≤2微克/毫升），包括那些对苯唑西林、环丙沙星、红霉素和螺旋霉素耐药的菌株。
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