哪些凝血因子会干扰一期凝血酶原时间？
Which coagulation factors interfere with the one-stage prothrombin time?
作者信息
Talstad I
机构信息
Medical Department B, Haukeland Hospital, University of Bergen, Norway.
出版信息
Haemostasis. 1993;23(1):19-25. doi: 10.1159/000216848.
Coagulation factors that interfere with the one-stage prothrombin time (PT) were investigated. PT responded with identical activities (adequately) against coagulation factors VII or X, only half as expected against factor IX, less than expected and nonlinearly against factor II. In multiple coagulation factor deficiencies PT did not differ from factor VII, which was the most reduced coagulation factor in warfarin therapy or liver disease. PT may also be influenced by factor VII at high activities.
对干扰一步法凝血酶原时间（PT）的凝血因子进行了研究。PT对凝血因子VII或X的反应具有相同活性（充分），对因子IX的反应仅为预期的一半，对因子II的反应低于预期且呈非线性。在多种凝血因子缺乏的情况下，PT与因子VII无差异，因子VII是华法林治疗或肝病中减少最多的凝血因子。高活性的因子VII也可能影响PT。
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